SAM-e (S-Adenosyl Methionine) is derived from the amino acids methionine and ATP (Adenosine Triphosphate). ATP is normally synthesized in the body but may become depleted from sickness and aging. SAM-e is concentrated in the liver and brain and has multiple mechanisms of action in the body. As a major methyl donor, it synthesizes hormones, nucleic acids, proteins, phospholipids, catecholamines, and other neurotransmitters.
SAM-e and Joint Function
In clinical trials, SAM-e has been shown to help reduce pain in joints and increase joint comfort and mobility by promoting the synthesis of proteoglycans, essential components of connective tissue.
SAM-e and Mood and Cognitive Function
SAM-e's ability to boost brain cell methylation facilitates youthful DNA enzymatic actions which may help account for its mood-elevating properties. These enzymatic actions are required for the healthy conversion of neurotransmitters, such a serotonin and dopamine. SAM-e also facilitates glutathione usage which improves the body's antioxidant defense and it helps maintain acetylcholine levels necessary for cognitive function.
SAM-e and Liver Function
In order to perform its detoxification role, SAME-e facilitates healthy methylation enzymatic processes and boost hepatic levels of glutathione, a critical antioxidant which helps protect against free radicals. SAME-e acts as a methyl donor in the synthesis an formation of phosphatidylcholine and L-cysteine, both necessary for maintaining liver health.
We using double –blister package to make sure that SAM-e coating tablet with stable high active.